Fermentation foam control | KEMAIX-103
KEMAIX-103 Fermentation Antifoam Manufacturer
Kemaix manufactures KEMAIX-103, a non-silicone polyether antifoam for industrial fermentation and bioprocess trials. Its documented 100 to 1,000 ppm range gives process teams a defined starting point for controlled screening.
A food-grade KEMAIX-103 option is available under the same grade code. Confirm the applicable standard, regulatory scope, and supporting documents for the intended use.
Product data
What Is Confirmed for KEMAIX-103?
KEMAIX-103 is an available non-silicone polyether antifoam for industrial fermentation and bioprocess evaluation. Its current independent TDS and SDS define the product identity and screening specifications below. Process performance still depends on application testing.
On smaller screens, scroll the table horizontally.
| Product type | Non-silicone polyether antifoam for industrial fermentation and bioprocess evaluation | KEMAIX-103 TDS |
|---|---|---|
| pH | 4.0 to 9.0 | KEMAIX-103 TDS |
| Viscosity | 100 to 1,000 mPa.s at 25 C | KEMAIX-103 TDS |
| Recommended dosage | 100 to 1,000 ppm; determine the working dose by application testing | KEMAIX-103 TDS |
| Packaging | 25 kg or 200 kg plastic drums; 1,000 kg IBC | KEMAIX-103 TDS |
| Shelf life | 12 months in unopened original packaging | KEMAIX-103 TDS |
| Chemical name | Glycerol, propoxylated, ethoxylated | KEMAIX-103 SDS |
| CAS number | 9082-00-2 | KEMAIX-103 SDS |
| Main substance listing | GLYCEROL PROPOXYLATE-B-ETHOXYLATE, 99.5% | KEMAIX-103 SDS |
Use the documented dosage as a screening range, not a fixed production formula. Match the supplied material to the current TDS and SDS, then test it under the intended medium and operating conditions.
Selection boundary
When to Evaluate a Non-Silicone Polyether Antifoam
Include a non-silicone polyether antifoam in the trial set when this chemistry matches the buyer’s selection brief. Final selection depends on the medium, foam pattern, dosing system, operating conditions, downstream requirements, and required documents.
Start with the medium and foam pattern
Record the process stage at which foam rises, such as charging, inoculation, peak aeration, or feed addition. Under the same test conditions, measure knockdown after addition, hold-down time, recurrence, and cumulative dose.
Check operating and downstream requirements
Include temperature, pH, agitation, aeration, batch duration, addition point, and dosing method in the test brief. If oxygen transfer, microbial growth, yield, sterilization, filtration, or purification affects approval, measure it in your own system.
Compare silicone, non-silicone, and hybrid candidates against the same baseline, dose logic, observation method, and acceptance criteria. Select from the resulting process data rather than chemistry labels alone.
Dosage screening
How to Set the Starting Dose
The KEMAIX-103 TDS lists a recommended dosage of 100 to 1,000 ppm and requires application testing. Use this range to design a controlled screen. It is not one fixed dose for every medium, vessel, or fermentation stage.
- Define whether ppm refers to total broth mass, initial charge, or another process basis.
- Run an untreated control under the same temperature, pH, agitation, aeration, fill level, and observation period.
- Select tiered points within 100 to 1,000 ppm and keep other controllable variables constant.
- Record initial, triggered, and repeat additions separately so cumulative dose remains visible.
- Record foam level, knockdown time, hold-down duration, recurrence, and cumulative dose at defined intervals.
Repeat the selected condition before scale-up. Set the next-scale starting point from controlled results and the process team’s risk assessment, not from the top or midpoint of the published range.
Application validation
Bench-Test and Scale-Up Validation Checklist
Use this buyer-run framework to evaluate KEMAIX-103 under your process conditions. Define the method and acceptance criteria before testing so foam-control observations and process results can support a scale-up decision.
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Define the baseline. Log vessel geometry, fill level, temperature, pH, agitation, aeration, feed timing, and the stage at which foam appears.
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Set tiered doses. Choose points within 100 to 1,000 ppm and use one calculation basis for every run.
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Measure foam response. Record knockdown, hold-down, recurrence, maximum foam level, repeat additions, and cumulative dose.
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Check process acceptance endpoints. Measure any oxygen-transfer, microbial, yield, sterilization, filtration, centrifugation, purification, or downstream endpoint required by your process team.
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Repeat the selected condition. Confirm whether the result is reproducible and retain lot, condition, timing, dose, observation, and deviation records.
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Plan the scale-up check. Account for vessel size, gas rate, impeller power, headspace, feed strategy, probe response, and dosing location.
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Align the purchase with the trial. Match the supplied KEMAIX-103, TDS and SDS, pack size, shelf life, and agreed supply conditions to the tested material.
Decision framework
Confirmed, Document-Gated, or Must Be Tested?
Separate product facts from inquiry-specific documentation and process results before selecting KEMAIX-103.
On smaller screens, scroll the table horizontally.
| Confirmed for KEMAIX-103 | Confirm for the inquiry | Test in your process |
|---|---|---|
| Non-silicone polyether antifoam for fermentation evaluation | Applicable food-related standard | Foam knockdown in the selected medium |
| pH 4.0 to 9.0 | Regulatory scope for the intended use and destination | Hold-down, recurrence, and cumulative dose |
| Viscosity 100 to 1,000 mPa.s at 25 C | Supporting food-related documents | Buyer-required oxygen-transfer, microbial, or yield endpoints |
| 100 to 1,000 ppm screening range | Current TDS/SDS, stock, MOQ, and lead time | Sterilization and downstream-process endpoints |
| 25/200 kg drums and 1,000 kg IBC | Quoted packaging and quantity | Reproducibility and scale-up performance |
| Same KEMAIX-103 code for the food-grade option | Food-related scope stated for the inquiry | Production dosing method and addition point |
Procurement FAQ
Food-Grade Option, Documents, Packaging and Supply
Does the food-grade option use a different grade code?
No. The food-grade option uses the same KEMAIX-103 grade code. Confirm the applicable standard, regulatory scope, and supporting documents for the intended use and destination before material approval.
Which product documents should I request?
Request the current KEMAIX-103 TDS and SDS for the quoted material. For food-related requirements, state the intended use, destination, required standard, and documentation needs with the inquiry.
What packaging and shelf life are documented?
The TDS lists 25 kg and 200 kg plastic drums and a 1,000 kg IBC. Shelf life is 12 months in unopened original packaging. Confirm the selected pack size and current availability on the quotation.
Can I request a sample?
Yes. Kemaix can provide a free 200 to 500 g KEMAIX-103 sample. Share the fermentation type, medium, operating conditions, current antifoam and dose, and document requirements.
What are the MOQ and lead time?
The general minimum for standard products is 200 kg. Standard stocked products are usually supplied in 7 to 10 working days. Confirm KEMAIX-103 stock, order terms, and lead time for the inquiry.
Request a trial
Request a KEMAIX-103 Sample and Document Check
Send your fermentation type, medium, batch size, temperature, pH, aeration rate, agitation conditions, foam pattern, addition point, current antifoam and dose, expected quantity, destination port, and any food-related requirement.
Kemaix will review the process conditions and confirm the sample, current TDS and SDS, packaging, stock, MOQ, and lead time for the inquiry.
